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WHAT IS IT?
Topiramate (Topamax) is an antiepileptic medication that works by blocking sodium channels and increasing GABA action.
WHEN DO WE USE IT?
Seizures: simple, complex, tonic-clonic (both generalized and focal)
Other: migraines (prophylaxis),pseudotumor cerebri, trigeminal neuralgia
WHEN DO WE AVOID USING IT?
In patients with known hypersensitivity to this medication.
HOW IS IT ADMINISTERED?
Administered orally without any regard to meals.
![Source](http://www.stepwards.com/wp-content/uploads/2016/07/HG_TopamaxTopiramate_size640x480.jpg)
HOW IS IT DOSED?
Typical adult dosage: 200-400 mg/day
WHAT ARE THE SIDE EFFECTS/TOXICITY?
Kidney stone formation: patients who are on this medication need to drink plenty of water!
Mental status: sedation, mental dulling, short-term memory loss, word-finding difficulties.
Numbness can be felt in the hands/feet as a result of using this medication.
General: weight loss
FURTHER READING
Page Updated: 07.27.2016