Quetiapine

WHAT IS IT?

Quetiapine (Seroquel) is an atypical antipsychotic. Its mechanism of action is not completely understood, however it is believed to have varied effects on 5-HT2, dopamine, alpha, and H1-receptors.

WHEN DO WE USE IT?

Schizophrenia, bipolar disorderobsessive compulsive disorder, anxiety disorder, depression, mania, Tourette syndrome.

WHEN DO WE AVOID USING IT?

In patients with known hypersensitivity to this medication.

HOW IS IT ADMINISTERED?

Orally administered 2-3 times a day (without regard to meals).

Source
Source
WHAT ARE THE SIDE EFFECTS/TOXICITY?

Prolonged QT interval

Cataracts

ANYTHING ELSE TO KEEP IN MIND?

Atypical antipsychotics have fewer extrapyramidal and anticholinergic side effects than traditional antipsychotics.

FURTHER READING

DynaMed

UpToDate

 

Page Updated: 06.19.2016