Page Contents
OVERVIEW
This page is dedicated to compiling Step 1 study notes for the topic of HIV medications. This page is likely disorganized as it was made in haste.
FUSION INHIBITORS
Examples:
- Maraviroc: inhibits attachment
- Enfuvirtide: inhibits penetration
INTEGRASE INHIBITORS
Examples:
- Dolutegravir
- Elvitegravir
- Raltegravir
PROTEASE INHIBITORS
Examples
Atazanavir, Darunavir, Fosamprenavir, Indinavir, Lopinavir, Ritonavir, Saquinavir (avir ending)
Mechanism
Inhibit HIV protease from calving the polypeptide products of HIV into their functional parts. Prevents maturation of new virus.
NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NNRTIs)
Examples
Nevirapine, efavirenz, dlavirdine
Mechanism
Important Facts
- Do not require activation via intracellular phosphorylation
- Adverse effects common: hepatic failure, Steven Johnson syndrome, topic epidermal necrolysis.
NRTIs)
Examples
Page Updated: 04.17.2017