This page is designed to organize content that is relevant to the topic of elevated liver enzymes over 1000. This is a rare lab value however requires a deliberate approach regardless.
WHAT EXACTLY IS IT?
Before going any farther, let us make sure we clearly define the “medical problem”. Elevated liver enzymes over 1000 refer to the presence of ALT or AST liver enzymes at concentrations great then 1000.
WHY IS IT A PROBLEM?
This magnitude of liver enzyme increase is suggestive of very severe liver damage.
ORGANIZING THE DIFFERENTIAL
There are only a few disease processes that can cause this type of liver enzyme elevation:
- Autoimmune hepatitis
- Acute viral hepatitis: CMV and EBV are also culprits here
- Acetaminophen toxicity
- Shock liver
Page Updated: 01.29.2017