Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the presence of autoantibodies against membrane phospholipids.
WHAT CAUSES IT?
This condition can occur in isolation or in association with systemic lupus erythematosus
WHY IS IT A PROBLEM?
The presence of these autoantibodies will cause for a hyper coagulable state to occur, resulting in vascular thrombosis events that can cause transit ischemic attacks, strokes, or DVT formation. Whats more, during pregnancy, this condition can cause complications (such as miscarriage/recurrent miscarriage).
Serology testing: the presence of the following antibodies are associated with APS:
- Anti-cardiolipin antibody
- Lupus anticoagulant
- Anti-beta2-glycoprotien antibody
HOW DO WE TREAT IT?
Anticoagulation therapies are utilized to manage this condition:
Page Updated: 10.02.2016