Page Contents
WHAT IS IT?
Vincristine is a microtubule inhibitor. It is a vinca alkalates that binds beta-tubulin and inhibits its polymerization into microbutubles. This ultimately prevents mitotic spend formation (will arrest cells in M-phase).
WHEN DO WE USE IT?
Solid tumors:
Leukemias:
Non-Hodgkin lymphomas:
WHEN DO WE AVOID USING IT?
HOW IS IT ADMINISTERED?
WHAT ARE THE SIDE EFFECTS/TOXICITY?
Peripheral neuropathy
ANYTHING ELSE TO KEEP IN MIND?
Page Updated: 04.23.2017