Rickets (Vitamin D Deficiency)

OVERVIEW

Rickets is a bone disorder in growing children that is characterized by deficient calcification of the growth plate.

WHAT CAUSES IT?

Vitamin D or calcium deficiency is often the cause of this condition.

WHAT MAKES US SUSPECT IT?

Risk Factors:

Dark skin complexion, exclusive breastfeeding, inadequate sun exposure, maternal vitamin D deficiency

Initial Presentation

Physical Exam:

HEENT:

  • Craniotabes (ping-pong ball skull)
  • Delayed fontanel closure/enlarged anterior fontanel

Musculoskeletal:

  • Chostochondral joint hypertrophy (rachitic rosary)
  • Long bone joint enlargement (wrist widening)
  • Bowed legs (genu varum)
CLINICAL WORKUP

Serum laboratory findings:

  • Calcium: normal/decrased
  • Phosphorous: normal/decreased
  • Alkaline phosphatase: increased
  • Parathyroid hormone: increased
  • 25-OH vitamin D: decreased

X-Ray imaging can show specific features of osteopenia, metaphysical cupping/fraying/epiphyseal widening

HOW DO WE PREVENT IT?

Vitamin D supplementation: babies who do not eat a vitamin D fortified baby formula can receive vitamin D supplementation to prevent rickets. While breast milk is the gold standard for nutrition in children < 1 age, it does not have adequate vitamin D.

ARCHIVE OF STANDARDIZED EXAM QUESTIONS

This archive compiles standardized exam questions that relate to this topic.

 

Page Updated: 11.22.2016