This page is dedicated to organizing various examples of standardized exam questions whose answer is multiple myeloma. While this may seem a odd practice, it is useful to see multiple examples of how multiple myeloma will be characterized on standardized exams (namely the boards and the shelf exams). This page is not meant to be used as a traditional question bank (as all of the answers will be the same), however seeing the classic “test” characterization for a disease is quite valuable.
KEY CHARACTERISTICS OF THIS CONDITION (ON EXAMS)
When it comes to standardized exams, each condition has its own “code” marked by key buzzwords, lab findings, clues, etc. If you are well versed in this code you will be able to more quickly identify the condition that is being discussed, and get the right answer on the exam you are taking. Below is the “code” for multiple myeloma.
- Hypercalcemia: is a common lab finding (not related to increased PTH)
- Bone lesions: these will be lytic in nature
- Renal insufficiency: the kidneys will be damaged by the deposition of immunoglobulins
- Monoclonal spike on serum protein electrophoresis: this is essentially diagnostic on exams for this condition. Often either IgG kappa or IgG lambda are elevated on this study.
Question # 1
Explanation # 1
Question # 2
Explanation # 2
TESTABLE FACTS ABOUT THIS CONDITION (BEYOND ITS IDENTIFICATION)
Many questions on standardized exams go beyond simply recognizing the underlying condition. Often there are specific testable facts regarding some aspect of the disease’s pathophysiology/management/clinical implications that are commonly asked. Some of these are listed below:
Page Updated: 04.09.2017