Repaglinide

WHAT IS IT?

Repaglinide (prandin) is a meglitinide analog that increases calcium in beta cells (causing the release of insulin). Works by inhibiting ATP-sensitive potassium channels.

WHEN DO WE USE IT? 

Type 2 diabetes mellitus

WHEN DO WE AVOID USING IT?

As sole therapy for type 1 diabetes mellitus

HOW IS IT ADMINISTERED?

Oral administration

Source
Source
WHAT ARE THE SIDE EFFECTS/TOXICITY?

Hypoglycemia, upper respiratory tract infection, headaches

ANYTHING ELSE TO KEEP IN MIND?

Not known if distributed into human milk (however shown to be distributed into the milk of rats)

FURTHER READING

DynaMed

UpToDate

Page Updated: 02.23.2016