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OVERVIEW
This page is dedicated to organizing various examples of standardized exam questions whose topic is leukocyte adhesion deficiency. While this may seem a odd practice, it is useful to see multiple examples of how leukocyte adhesion deficiency will be characterized on standardized exams (namely the boards and the shelf exams). This page is not meant to be used as a traditional question bank (as all of the answers will be the same), however seeing the classic “test” characterization for a topic is quite valuable.
KEY CHARACTERISTICS OF THIS CONDITION (ON EXAMS)
When it comes to standardized exams, each topic has its own “code” marked by key buzzwords, lab findings, clues, etc. If you are well versed in this code you will be able to more quickly identify the condition that is being discussed, and get the right answer on the exam you are taking. Below is the “code” for leukocyte adhesion deficiency.
- Delayed separation of umbilical cord: is a classic clue in the medical history
- Recurrent bacterial infections may be a component of the history.
- Lack of pus formation during infections is a classic hint
- Increased circulation of neutrophils can be detected in the serum
- Absence of neutrophils in the dermis/epidermis: can be noticed histologically.
QUESTION EXAMPLES
Question # 1
Explanation # 1
Question # 2
Explanation # 2
TESTABLE FACTS ABOUT THIS TOPIC (BEYOND ITS IDENTIFICATION)
Many questions on standardized exams go beyond simply recognizing the underlying topic. Often there are specific testable facts regarding some aspect of the topic’s pathophysiology/management/clinical implications that are commonly asked. Some of these are listed below:
- Cause: most commonly caused by a defect of interns (CD18 subunit)
- Inheritance pattern: autosomal recessive
- Consequence: impaired adhesion of marginated pool of leukocytes.
Page Updated: 04.26.2017