Osteosarcoma

OVERVIEW

An osteosarcoma refers to a malignant primary bone tumor.

WHAT MAKES US SUSPECT IT?

Risk Factors:

Teenage boys,

Initial Presentation

  • Tender soft tissue mass
  • Absence of “constitutional symptoms”: no fever, weight loss, malaise, night sweats
CLINICAL WORKUP

Serum values:

  • Alkaline phosphatase: elevated from increased turnover of damaged osteocytes
  • Lactate dehydrogenase: elevated from increased turnover of damaged osteocytes

X-Ray imaging may reveal:

  • Spiculated “sunburst” pattern
  • Periosteal elevation (Codman triangle)
TREATMENT

Tumor excision 

Chemotherapy 

OTHER INFO

Most common primary bone tumor affecting children and young adults.

ARCHIVE OF STANDARDIZED EXAM QUESTIONS 

This archive compiles standardized exam questions that relate to this topic.

 

Page Updated: 11.22.2016